Blood Pressure and Poppers
I have been using as well as making poppers for 12 years. During the last decade, I have combed the web searching for specific information about the various nitrites, but I haven't found anything that says what I have been forced to discover on my own. Certainly, there has been the long-standing gay legend that amyl nitrite, when it was legal OTC, was the best popper. But never was there a reason why. I am fairly confident that I know why now.
Maintaining a certain blood pressure range is vital for human life. It fluctuates, but if it goes too low, the brain can't get enough blood, which can cause fainting coma or death. Trauma victims go into shock when they've lost too much blood because their hearts and vasoconstriction can't maintain a high enough blood pressure to keep blood circulating effectively.
That said, all poppers reduce blood pressure. My blood pressure runs normal 120/70. What I have found, and this applies to my own personal experience, is that the lower carbon nitrites reduce my blood pressure more than the higher ones. It's progressive based upon a number of carbon. So...the sequence would be - ethyl nitrite(2), isopropyl(3), butyl/isobutyl(4), amyl, isoamyl(5). I have used all of those nitrites and ET has by far the worst effect on blood pressure. I literally had to sit down for an hour after only a few minute's worths of whiffing. I felt very sick. Any further whiffing attempts would have made me pass out. Isopropyl nitrite ALWAYS makes my blood pressure cave, usually within 5 to 10 minutes. Butyl/isobutyl are next in line. It might take a little longer with these two to cave my blood pressure, but it's bound to happen sooner or later, usually within 15 minutes. Amyl/isoamyl nitrite has never caved my blood pressure, although they have made it get a little whacky after a session. For example, when I squat down and stand up quickly, my blood pressure takes longer to adjust.
Long story short.....the major reason amyl nitrite makes the best popper is simply because it doesn't cave my blood pressure. I can have frequent sessions without dreading this side effect. Additionally, it has great effects and a very mild odor compared to the others.
Now....as I have stated, these are the effects these poppers have had on me. Others may have a different experience. Other people may or may not experience the same blood pressure effects as I do upon inhaling the various poppers. One other point is that the presence of impurities, such as nitric acid, seems to amplify the toxic effect of caving the blood pressure. Other impurities may do likewise. It's a subject worth investigating.
What about pentyl/isopentyl like Radkal Rush or Titanium?
Those really messed me up, as I could keep hitting them. And the weaker I got the more I would listen to humiliation and impotence-focused femdom material. It was a horrible downward spiral that was very difficult to get out of.
Pentyl(amyl) and isopentyl(isoamyl) are very similar. They have yet to cave my blood pressure even with steady hitting. For me, it appears that I can tolerate a continuous amount of amyls. That said, if I were to suddenly start having toxic effects from the amyls, I would suspect two things.....it's not amyl....or it has major impurities.